Food and nutrients either directly or indirectly through genetic variation in the humans can lead to pathogenesis of a variety of diseases, including cardiometabolic, psychosomatic, somato-psychic and even malignant aliments. Though, nutrients and foods usually interact with genes in a benign manner, but sometimes, this interaction can have fatal outcomes”1 Therefore, diet, genetics and disease studies are gaining significance world over with the coming up of ever newer evidences that “nutrition can contribute to disease pathogenesis directly as well as indirectly genetic variation2.Increasing number of cardiometabolic deaths are largely linked to eating habits of people. Nutrigenomic and nutrigenetic studies have been exploring interaction between nutrients and genes. In view of this, the Pacific Group of Universities proposes to study food borne, dietary, nutritional, nutrigenomic and nutrigenetic etiology of aliments and diseases along with an international conference.

01-03

We are now in an era of integrated Biomedical Engineering and Medicine, resulting in STEM model (or format) of Medicine or STEM2, which can be incorporated into both education and clinical care. This paper is about the new formats of Biomedical Engineering departments, involving Biomedical Engineering in Medicine program, which can enable BME departments to be actively involved with medical schools in R&D, and with hospitals in implementing research developments and medical devices in clinical care.

04-10

The obstructed inguinal hernia presenting with acute abdomen is often encountered in surgical emergency. The diagnosis is mostly clinical and emergency surgery has always been the cornerstone of its management. We are hereby reporting a case of obstructed left inguinal hernia presenting with unique set of co- morbidities which ruled out the possibility of emergency surgery since the patient was on anti- fibrinolytic agents post percutaneous transluminal coronary angiography (PTCA), laparoscopic approach was also ruled out since the patient had very low EF of 30% and yet the surgical team needed to manage the patient for both the intestinal obstruction as well as for the definitive management of the hernia.

11-14

Giant fibroadenomas are a rare form of fibroadenoma presenting as rapidly enlarging breast masses. Typically, greater than 5 cm or 500 grams in size and most frequently seen in premenopausal Afro-Caribbean or East Asian females. Giant juvenile fibroadenoma in adolescents should be dealt with utmost caution as this may be associated with anxiety, fear, and emotional distress. Aim of treatment is preserving the normal contour of the breast along with a good cosmetic scar. We are hereby describing a step-by-step scheme for removal of such large masses via a small cosmetic circumareolar incision ensuring an optimal balance between complete resection and acceptable cosmetic outcome for a developing breast.

15-18

A 72-Year-Old male presented with exertional dyspnoea and bilateral pedal oedema since 6 months. On taking history it was found that the patient underwent pneumonectomy in 1963 and had been living a normal life since then. Patient had developed fibro-caseous tuberculosis at the age of 16 years. Due to fibrotic bands and adhesions the treating doctor decided to remove the entire lung as it was unsalvageable. Patient was further managed with 2nd Line ATTs and other supportive care during his 6-month long hospital stay at the time of surgery. Patient served as a government employee for 56 years. Survival for 56 years that too with normal activities of daily life is a rare phenomenon after pneumonectomy. He gradually developed Chronic Obstructive Pulmonary Disease and eventually landed up in Cor-Pulmonale and CHF.

19-23

Oculocutaneous albinism (OCA) is an autosomal recessive disorder which is characterized by reduced or complete lack of melanin pigment in the skin, hair and eyes. These disorders are classified as syndromic OCA and non-syndromic OCA. Non-syndromic OCA are divided into 8 subtypes from OCA1 to OCA8. The symptoms range from characteristic pale or white skin, hair, eye with poor visual acuity, photophobia and nystagmus. Due to clinical overlap between OCA subtypes, molecular diagnosis is necessary to establish the gene defect. This reduction or absence of melanin causes albinos to be highly susceptible for all types of solar damages such as pachydermia, actinic keratoses, solar lentigines, solar erythema and cutaneous malignancies such as squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and melanoma.

24-32

Turner Syndrome is the most common genetic anomaly manifesting in females as primary ovarian failure, Infertility and short stature. There are numerous systemic manifestations reported with Turner Syndrome. Here we present a case of 19-Year-old female, diagnosed with Turner syndrome but with two uncommon features. Recurrent anaemia and jaundice. Genetic anomaly associated with Dimorphic anaemia and Hepatic derangement can be an isolated incidence here or an associative factor, further clinical research is required to derive an outcome.

33-37

Mindfulness Based Interventions (MBIs) have potential for cultivating optimal educational needs such as learning, teaching and well-being outcomes in schools. MBIs in schools have increasingly demonstrated acceptability among school based well-being programs and have revealed empirical evidence of their efficacy. Given the developmental significance of childhood and early adolescence periods, it is important to understand and promote their mental health and well being aspects. MBIs in schools have shown their effectiveness in minimizing mental health risk and thereby promoting well being aspects not only in students but teachers also. However, to date researches on MBIs in schools have yielded varying degrees of effects across grades or levels of school education that create confusion in their universal health and well being promotion. The review aims at advancing the current understanding of MBIs for school children and adolescents by focusing on the identified empirical and methodological limitations along with the benefits of MBIs in school set ups. In addition, the article describes the current challenges and directions for future research attempts.

38-45

Boerhavia diffusa L. (Family – Nyctaginaceae), is commonly known as Horse Purslane, Pigweed, Punarnava, Shophaghni, Kathila, Shilatika, etc. It is a small, creeping perennial herb with little pinkish flowers and found throughout in India, tropical and subtropical Asia, Africa, Australia and America. Leaves and whole plant of B. diffusa are consumed in daily diet by various ethnic communities of India. Medicinally, it is used for treatment of several diseases for example, anemia, asthma, blood impurity, body pain, cough, rheumatism, gall bladder stone, jaundice, joint pain, heart disease, enlargement of liver and spleen etc.

Dealing with social context diversity is acknowledged as a challenging aspect for most of clinical patients. Non-pharmacological interventions that include social cognitive training across various chronic clinical conditions have increased dramatically over the past few years. In the present review, we have attempted to provide an overview of various evidenced-based social cognitive interventions (SCIs) targeting single and multiple social cognitive domains in a variety of developmental and neuro-psychiatric conditions. We have attempted to include all the existing interventions and summarize the empirical basis of these SCIs. The current review aims at advancing the current understanding of SCIs across various clinical and neuro-developmental conditions by focusing on their treatment benefits, limitations, current challenges and directions for future research.

61-64

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